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Jie Dong

Associate Professor

Fermentation Science

Phone:

(618) 650-3559 (office)

Email:

Address:

Department of Chemistry
3200 Science West

44 South Circle Drive

Southern Illinois University Edwardsville
Edwardsville, IL  62026

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Education

  • Ph.D., Chemical & Biomolecular Engineering, The Ohio State University, Columbus, OH, May 2014  

Thesis: "Butanol Production from lignocellulosic biomass"

Advisor: Dr. Shang-Tian Yang

  • M.S., Chemical Engineering, Zhejiang University, Hangzhou, China, June 2010 

Thesis: "Emulsion and Miniemulsion Polymerization in Taylor Reactor"

  • B.S., Chemical Engineering and Technology, Zhejiang University, Hangzhou, China, June 2007

Thesis: "Inverse-suspension Polymerization of 1,1,3,3-Tetramethylguandium Acrylate and the SO2 Sorption Behaviors of the Resulting Crosslinked Polymer Particles"

Work Experience

August 2018 - Present

April 2015 - July 2018

Assistant Professor/ Fermentation Scientist, Southern Illinois University Edwardsville/ National Corn to Ethanol Research Center, Edwardsville, IL.

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  • Lignocellulosic biomass and municipal solid waste hydrolysis with high solid loadings

  • Synthesis of value-added chemicals (butanol, isoprenol, ethanol) and materials (polyhydroxyalkanoates) through microbial fermentation processes from biomass

  • Enzyme production and immobilization (Lipase)

  • Study of microorganisms (Clostridia, Lactic acid bacteria, E. coli, C. necator, P. putida) metabolic networks and engineering of pathways

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Postdoctoral Fellow, Lawrence Berkeley National Laboratory, Joint BioEnergy Institute, Emeryville, CA.

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  • Studied the aromatic metabolism and carbon mass balance in Ralstonia eutropha H16 and Pseudomonas putida KT2440 with the engineered methyl ketone pathways.

  • Optimized the biofuel production process, including feedstock pretreatment, cellulose/hemicellulose saccharification, base-catalyzed depolymerization of lignin, and the fermentation to methyl ketones.

  • Designed a one-pot process for converting engineered plant biomass (Arabidopsis, switchgrass, and sorghum) to biofuel (methyl ketones).

Publications

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  1. Dong J, Fakhari M, Ban L, Polhemus K, Shehu MR, Doustkhahvajari F, Kukielski P, Venigalla A, Lash T, Sathitsuksanoh N, Zhang Y. High-efficiency conversion of corn bran to ethanol at 150 L scale, Bioresource Technology, 2024, 408:131216.

  2. Kukielski P., Lilia Ban L., Polhemus K., Shehu M. R., Venigalla A., Lasseigne K., Ma M., Zhang Y., Dong J.  Co-Production of Ethanol from Starch and Cellulose in Corn during Simultaneous Saccharification and Fermentation. Industrial Biotechnology 2023 19:3, 163-167.

  3. Dong J, Kim D., Yoo C.G. Editorial: Biochemical/biomaterial production from lignocellulosic biomass. Front. Chem. Eng. 2023. 5:1266904. doi: 10.3389/fceng.2023.1266904

  4. Hossain M.A., Mushill L., Rahaman M.S., Tulaphol S., Mains S.M., Vickers T., Tulaphol A, Dong J., and Sathitsuksanoh N. Upcycling agricultural waste to biodegradable polyhydroxyalkanoates by combined ambient alkaline treatment and bacterial fermentation, Ind. Crops Prod. 2022, 185, 114867.

  5. Pruksasri S., Stauffer N., Hall C., Hafner J., Dong J. Key Enzymes in biorefinery, Chapter in A-Z of Biorefinery: A Comprehensive View, Edited by Tongchul N. et al., 2022, Elsevier Inc. ISBN: 978-0-12-819248-1.

  6. Barcelos C., Oka A., Yan J., Das L., Achinivu E., Magurudenia H., Akdemir S., Dong J., Baral N., Yan C., Scown C., Tanjore D., Sun N., Simmons B., Gladden J. Sundstrom E., High-efficiency conversion of ionic liquid-pretreated woody biomass to ethanol at pilot scale, ACS Sustainable Chemistry & Engineering, 2021, 9 (11), 4042-4053.

  7. Hossain M.A., Rahaman M.S., Yelle D., Shang H., Sun Z., Renneckar S., Dong J., Tulaphol S., Sathitsuksanoh N. Effects of polyol-based deep eutectic solvents on the efficiency of rice straw enzymatic hydrolysis. Ind. Crops Prod. 2021, 167, 113480.

  8. Hossain, M., Mills, K., Molley, A., Rahaman, M., Tulaphol, S., Lalvani, S., Dong, J., Sunkara, M., Sathitruksanoh, N. Catalytic isomerization of dihydroxyacetone to lactic acid by heat treated zeolites. Applied Catalysis A, General, 2021, 611, 117979.

  9. Dong, J., Chen Y., Benites V., Baidoo, E., Petzold, C., Beller H., Eudes A., Scheller, H., Adams, P., Mukhopadhyay, A., Simmons, B., Singer S. Methyl ketone production by Pseudomonas putida is enhanced by plant derived amino acids. Biotechnology and Bioengineering, 2019, 116: 1909-1922.

  10. Li, J., Du, Y., Bao, T., Dong, J., Lin, M., Shim, H., Yang, S. T. n-Butanol production from lignocellulosic biomass hydrolysates without detoxification by Clostridium tyrobutyricum Δack-adhE2 in a fibrous-bed bioreactor. Bioresource Technology. 2019, 289: 121749.

  11. Wang, S., Cheng G., Dong J., Tian T., Lee, T.S., Mukhopadhyay A., Simmons B., Yuan, Q., Singer, S.W. NaCl enhances E. coli growth and isoprenol production in the presence of imidazolium-based ionic liquids. Bioresource Technology Reports, 2019, 6: 1-5.

  12. Wang, S., Cheng G., Dong J., Tian T., Lee, T.S., Mukhopadhyay, A., Simmons, B.A., Yuan, Q., Singer, S.W. Tolerance characterization and isoprenol production of adapted Escherichia coli in the presence of ionic liquids. ACS Sustainable Chem. Eng. 2019, 7, 1457-1463.   

  13. Yu, L., Zhao, J., Xu, M., Dong, J., Varghese, S. Yu, M., Tang, I-C., Yang, S. T. Metabolic engineering of Clostridium tyrobutyricum for n-butanol production: Effects of CoA transferase. Appl. Microbiol. Biotechnol., 2015, 99(11): 4917-4930.

  14. Dong, J., Du, Y., Zhou, Y., Yang, S. T. Butanol production from soybean hull and soy molasses by acetone butanol ethanol fermentation, Chapter 2, Soy-based Chemicals and Materials: Growing the Supply Chain, American Chemical Society Symposium Series 2014, 1178: 25-41.

  15. Lu, C., Dong, J., Yang, S. T. Butanol production from wood pulping hydrolysate in an integrated fermentation-gas stripping process, Bioresource Technology. 2013, 143: 467-475.

  16. Dong, J., Wu, L., An, D., Li, B., Zhu, S., Stability study of inverse suspension copolymerization of 1,1,3,3-tetramethylguandium acrylate and N,N'-methylene bisacrylamide, Journal of Applied Polymer Science. 2010, 118(3):1450-1454.

Grants

  • Department of Energy, ARPA-E, $1,600,000. A Novel Integrated Fermentation Process with Engineered Microbial Consortia for Butanol Production from Lignocellulose Sugars without CO2 Emission, 08/2021-07/2024.

PI: Shang-Tian Yang, The Ohio State University

Co-PIs:

Jie Dong

Ting Lu, University of Illinois Urbana-Champaign

  • United States Department of Agriculture, AFRI, $800,000. Production of Butyrate, Butanol, And Butyl Butyrate from Lignocellulosic Biomass, 05/2022-04/2025.

PI: Shang-Tian Yang, The Ohio State University

Co-PI: Jie Dong

  • Department of Energy, BETO, $2,500,000. Metabolic and process engineering of solventogenic clostridia for stable, continuous n-butanol production from lignocellulosic biomass hydrolysate, 10/2022-09/2025.

PI: Shang-Tian Yang, The Ohio State University

Co-PIs:

Jie Dong

Maobing Tu, University of Cincinnati

Deepti Tanjore, ABPDU

Marceline Egnin, Tuskegee University

  • NSF. $500,000. FMSG: Bio: Integrated bioprocess and synthetic biology for future biomanufacturing of industrial products. 10/2023-09/2025.

PI: Shang-Tian Yang, The Ohio State University

Co-PI: Jie Dong

  • NSF. $745,000. ExpandQISE: Track 1: Investigating biomass pretreatment with nanodiamond quantum sensors. 10/2023-09/2026.

PI: Jie Dong

Co-PI: Chong Zu, Washington University in St. Louis

 

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